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One example is, to change the dose of Compound A useful for a mouse (twenty mg/kg) to some dose according to the BSA for just a rat, multiply 20 mg/kg by the Km component for any mouse after which divide by the Km issue for a rat. This calculation results in a rat equal dose for Compound A of 10 mg/kg.1 for binding (Figure 2G). The incompatible res

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